Catalytic Enantioselective Intramolecular Oxa-Michael Reaction to α,β-Unsaturated Esters and Amides

[Image: see text] A bifunctional iminophosphorane (BIMP)-catalyzed, enantioselective intramolecular oxa-Michael reaction of alcohols to tethered, low electrophilicity Michael acceptors is described. Improved reactivity over previous reports (1 day vs 7 days), excellent yields (up to 99%), and enanti...

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Detalles Bibliográficos
Autores principales: Su, Guanglong, Formica, Michele, Yamazaki, Ken, Hamlin, Trevor A., Dixon, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273320/
https://www.ncbi.nlm.nih.gov/pubmed/37253087
http://dx.doi.org/10.1021/jacs.3c03182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273320/
https://www.ncbi.nlm.nih.gov/pubmed/37253087
http://dx.doi.org/10.1021/jacs.3c03182

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