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HspB8 interacts with BAG3 in a “native‐like” conformation forming a complex that displays chaperone‐like activity

The HspB8‐BAG3 complex plays an important role in the protein quality control acting alone or within multi‐components complexes. To clarify the mechanism underlying its activity, in this work we used biochemical and biophysical approaches to study the tendency of both proteins to auto‐assemble and t...

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Detalles Bibliográficos
Autores principales: Sciandrone, Barbara, Ami, Diletta, D'Urzo, Annalisa, Angeli, Elena, Relini, Annalisa, Vanoni, Marco, Natalello, Antonino, Regonesi, Maria Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273338/
https://www.ncbi.nlm.nih.gov/pubmed/37243950
http://dx.doi.org/10.1002/pro.4687