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gyrA Mutations in Mycoplasma genitalium and Their Contribution to Moxifloxacin Failure: Time for the Next Generation of Resistance-Guided Therapy

BACKGROUND: Although single nucleotide polymorphisms (SNPs) in Mycoplasma genitalium parC contribute to fluoroquinolone treatment failure, data are limited for the homologous gene, gyrA. This study investigated the prevalence of gyrA SNPs and their contribution to fluoroquinolone failure. METHODS: S...

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Detalles Bibliográficos
Autores principales: Murray, Gerald L, Plummer, Erica L, Bodiyabadu, Kaveesha, Vodstrcil, Lenka A, Huaman, Jose L, Danielewski, Jennifer A, Chua, Teck Phui, Machalek, Dorothy A, Garland, Suzanne, Doyle, Michelle, Sweeney, Emma L, Whiley, David M, Bradshaw, Catriona S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273371/
https://www.ncbi.nlm.nih.gov/pubmed/36722416
http://dx.doi.org/10.1093/cid/ciad057