Cargando…
Big versus small: The impact of aggregate size in disease
Protein aggregation results in an array of different size soluble oligomers and larger insoluble fibrils. Insoluble fibrils were originally thought to cause neuronal cell deaths in neurodegenerative diseases due to their prevalence in tissue samples and disease models. Despite recent studies demonst...
Autores principales: | Hnath, Brianna, Chen, Jiaxing, Reynolds, Joshua, Choi, Esther, Wang, Jian, Zhang, Dongyan, Sha, Congzhou M., Dokholyan, Nikolay V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273386/ https://www.ncbi.nlm.nih.gov/pubmed/37243896 http://dx.doi.org/10.1002/pro.4686 |
Ejemplares similares
-
NeuralDock: Rapid and Conformation-Agnostic Docking of Small Molecules
por: Sha, Congzhou M., et al.
Publicado: (2022) -
Differentiable rotamer sampling with molecular force fields
por: Sha, Congzhou M., et al.
Publicado: (2023) -
Quantifying network behavior in the rat prefrontal cortex: a reproducibility crisis
por: Sha, Congzhou M., et al.
Publicado: (2023) -
Adaptation‐Proof SARS‐CoV‐2 Vaccine Design
por: Vishweshwaraiah, Yashavantha L., et al.
Publicado: (2022) -
How big is big and how small is small: the sizes of everything and why
por: Smith, Timothy Paul
Publicado: (2013)