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A whole transcriptome profiling analysis for antidepressant mechanism of Xiaoyaosan mediated synapse loss via BDNF/trkB/PI3K signal axis in CUMS rats

BACKGROUND: Depression is a neuropsychiatric disease resulting from deteriorations of molecular networks and synaptic injury induced by stress. Traditional Chinese formula Xiaoyaosan (XYS) exert antidepressant effect, which was demonstrated by a great many of clinical and basic investigation. Howeve...

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Detalles Bibliográficos
Autores principales: Meng, Pan, Zhang, Xi, Liu, Tong-tong, Liu, Jian, Luo, Yan, Xie, Ming-xia, Yang, Hui, Fang, Rui, Guo, Dong-wei, Zhong, Zi-yan, Wang, Yu-hong, Ge, Jin-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273699/
https://www.ncbi.nlm.nih.gov/pubmed/37322430
http://dx.doi.org/10.1186/s12906-023-04000-0