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The role of rhIGF-1/BP3 in the prevention of pulmonary hypertension in bronchopulmonary dysplasia and its underlying mechanism

BACKGROUND: This study aimed to determine whether postnatal treatment with recombinant human IGF-1 (rhIGF-1)/binding peptide 3 (BP3) ameliorates lung injury and prevents pulmonary hypertension (PH) in bronchopulmonary dysplasia (BPD) models. METHODS: We used two models of BPD in this study: one mode...

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Detalles Bibliográficos
Autores principales: Qu, Sehua, Shan, Lianqiang, Chen, Xin, Zhang, Zhen, Wu, Yumeng, Chen, Yun, Zhuo, Feixiang, Wang, Yitong, Dong, Huaifu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273711/
https://www.ncbi.nlm.nih.gov/pubmed/37322452
http://dx.doi.org/10.1186/s12890-023-02498-1