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Interactions between selectivity filter and pore helix control filter gating in the MthK channel
K(+) channel activity can be limited by C-type inactivation, which is likely initiated in part by dissociation of K(+) ions from the selectivity filter and modulated by the side chains that surround it. While crystallographic and computational studies have linked inactivation to a “collapsed” select...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274084/ https://www.ncbi.nlm.nih.gov/pubmed/37318452 http://dx.doi.org/10.1085/jgp.202213166 |