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GATA6-AS1 Regulates Intestinal Epithelial Mitochondrial Functions, and its Reduced Expression is Linked to Intestinal Inflammation and Less Favourable Disease Course in Ulcerative Colitis

BACKGROUND AND AIMS: Widespread dysregulation of long non-coding RNAs [lncRNAs] including a reduction in GATA6-AS1 was noted in inflammatory bowel disease [IBD]. We previously reported a prominent inhibition of epithelial mitochondrial functions in ulcerative colitis [UC]. However, the connection be...

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Detalles Bibliográficos
Autores principales: Sosnovski, Katya E, Braun, Tzipi, Amir, Amnon, Moshel, Danielle, BenShoshan, Marina, VanDussen, Kelli L, Levhar, Nina, Abbas-Egbariya, Haya, Beider, Katia, Ben-Yishay, Rakefet, Asad Ali, Syed, Moore, Sean R, Kugathasan, Subra, Abramovich, Ifat, Glick Saar, Efrat, Weiss, Batya, Barshack, Iris, Gottlieb, Eyal, Geiger, Tamar, Ben-Horin, Shomron, Ulitsky, Igor, Hyams, Jeffrey S, Denson, Lee A, Haberman, Yael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274303/
https://www.ncbi.nlm.nih.gov/pubmed/36655602
http://dx.doi.org/10.1093/ecco-jcc/jjad006