Impaired Thiamine Metabolism in Amyotrophic Lateral Sclerosis and Its Potential Treatment With Benfotiamine: A Case Report and a Review of the Literature

Homogenates of brain tissue from the frontal cortex at autopsy in patients with amyotrophic lateral sclerosis (ALS) showed dramatically reduced levels of the enzyme thiamine pyrophosphatase (TPPase), the enzyme responsible for the conversion of thiamine pyrophosphate (TPP) to thiamine monophosphate...

Descripción completa

Detalles Bibliográficos
Autor principal: Mann, Richard H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274516/
https://www.ncbi.nlm.nih.gov/pubmed/37333039
http://dx.doi.org/10.7759/cureus.40511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274516/
https://www.ncbi.nlm.nih.gov/pubmed/37333039
http://dx.doi.org/10.7759/cureus.40511

Ejemplares similares