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Preclinical characterization of WB737, a potent and selective STAT3 inhibitor, in natural killer/T‐cell lymphoma

Natural killer/T‐cell lymphoma (NKTL) is an uncommon malignancy with poor prognosis and limited therapeutic options. Activating mutations of signal transducer and activator of transcription 3 (STAT3) are frequently found in patients with NKTL, suggesting that targeted inhibition of STAT3 is a potent...

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Detalles Bibliográficos
Autores principales: Wang, Yali, Zhou, Wenbo, Chen, Jianfeng, Chen, Jinghong, Deng, Peng, Chen, Huang, Sun, Yichen, Yu, Zhaoliang, Pang, Diwen, Liu, Lizhen, Wang, Peili, Hong, Jing Han, Teh, Bin Tean, Huang, Huiqiang, Li, Wenyu, Yi, Zhengfang, Lim, Soon Thye, Chen, Yihua, Ong, Choon Kiat, Liu, Mingyao, Tan, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274570/
https://www.ncbi.nlm.nih.gov/pubmed/37334274
http://dx.doi.org/10.1002/mco2.284