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Methoxsalen inhibited the acquisition of nicotine self-administration: attenuation by cotinine replacement in rats

Cigarette smoking remains the leading preventable cause of disease and death. Nicotine is the primary reinforcing ingredient in cigarettes sustaining addiction. Cotinine is the major metabolite of nicotine that produces a myriad of neurobehavioral effects. Cotinine supported self-administration and...

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Detalles Bibliográficos
Autores principales: Ding, Zheng-Ming, Neslund, Elizabeth M., Sun, Dongxiao, Tan, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274622/
https://www.ncbi.nlm.nih.gov/pubmed/37333320
http://dx.doi.org/10.1101/2023.06.04.543614