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Methoxsalen inhibited the acquisition of nicotine self-administration: attenuation by cotinine replacement in rats
Cigarette smoking remains the leading preventable cause of disease and death. Nicotine is the primary reinforcing ingredient in cigarettes sustaining addiction. Cotinine is the major metabolite of nicotine that produces a myriad of neurobehavioral effects. Cotinine supported self-administration and...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274622/ https://www.ncbi.nlm.nih.gov/pubmed/37333320 http://dx.doi.org/10.1101/2023.06.04.543614 |