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Novel Roles for Diacylglycerol in Synaptic Vesicle Priming and Release Revealed by Complete Reconstitution of Core Protein Machinery

Here we introduce the full functional reconstitution of genetically-validated core protein machinery (SNAREs, Munc13, Munc18, Synaptotagmin, Complexin) for synaptic vesicle priming and release in a geometry that enables detailed characterization of the fate of docked vesicles both before and after r...

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Detalles Bibliográficos
Autores principales: Sundaram, R Venkat Kalyana, Chatterjee, Atrouli, Bera, Manindra, Grushin, Kirill, Panda, Aniruddha, Li, Feng, Coleman, Jeff, Lee, Seong, Ramakrishnan, Sathish, Ernst, Andreas M., Gupta, Kallol, Rothman, James E., Krishnakumar, Shyam S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274626/
https://www.ncbi.nlm.nih.gov/pubmed/37333317
http://dx.doi.org/10.1101/2023.06.05.543781