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Bacterial mimicry of eukaryotic HECT ubiquitin ligation

HECT E3 ubiquitin (Ub) ligases direct their modified substrates toward a range of cellular fates dictated by the specific form of monomeric or polymeric Ub (polyUb) signal that is attached. How polyUb specificity is achieved has been a longstanding mystery, despite extensive study ranging from yeast...

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Detalles Bibliográficos
Autores principales: Franklin, Tyler G., Brzovic, Peter S., Pruneda, Jonathan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274628/
https://www.ncbi.nlm.nih.gov/pubmed/37333152
http://dx.doi.org/10.1101/2023.06.05.543783