Myeloid cell influx into the colonic epithelium is associated with disease severity and non-response to anti-Tumor Necrosis Factor Therapy in patients with Ulcerative Colitis

Ulcerative colitis (UC) is an idiopathic chronic inflammatory disease of the colon with sharply rising global prevalence. Dysfunctional epithelial compartment (EC) dynamics are implicated in UC pathogenesis although EC-specific studies are sparse. Applying orthogonal high-dimensional EC profiling to...

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Detalles Bibliográficos
Autores principales: Jha, Divya, Al-Taie, Zainab, Krek, Azra, Eshghi, Shadi Toghi, Fantou, Aurelie, Laurent, Thomas, Tankelevich, Michael, Cao, Xuan, Meringer, Hadar, Livanos, Alexandra E, Tokuyama, Minami, Cossarini, Francesca, Bourreille, Arnaud, Josien, Regis, Hou, Ruixue, Canales-Herrerias, Pablo, Ungaro, Ryan C., Kayal, Maia, Marion, James, Polydorides, Alexandros D, Ko, Huaibin M., D’souza, Darwin, Merand, Raphael, Kim-Schulze, Seunghee, Hackney, Jason A., Nguyen, Allen, McBride, Jacqueline M., Yuan, Guo-Cheng, Colombel, Jean Frederic, Martin, Jerome C., Argmann, Carmen, Suárez-Fariñas, Mayte, Petralia, Francesca, Mehandru, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274630/
https://www.ncbi.nlm.nih.gov/pubmed/37333091
http://dx.doi.org/10.1101/2023.06.02.542863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274630/
https://www.ncbi.nlm.nih.gov/pubmed/37333091
http://dx.doi.org/10.1101/2023.06.02.542863

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