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A novel deep proteomic approach in human skeletal muscle unveils distinct molecular signatures affected by aging and resistance training

We examined the myofibrillar (MyoF) and non-myofibrillar (non-MyoF) proteomic profiles of the vastus lateralis (VL) muscle of younger (Y, 22±2 years old; n=5) and middle-aged participants (MA, 56±8 years old; n=6), and MA following eight weeks of knee extensor resistance training (RT, 2d/week). Shot...

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Detalles Bibliográficos
Autores principales: Roberts, Michael D., Ruple, Bradley A., Godwin, Joshua S., McIntosh, Mason C., Chen, Shao-Yung, Kontos, Nicholas J., Agyin-Birikorang, Anthony, Max Michel, J., Plotkin, Daniel L., Mattingly, Madison L., Brooks Mobley, C., Ziegenfuss, Tim N., Fruge, Andrew D., Kavazis, Andreas N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274632/
https://www.ncbi.nlm.nih.gov/pubmed/37333259
http://dx.doi.org/10.1101/2023.06.02.543459