Interleukin-21 Drives a Hypermetabolic State and CD4(+) T Cell-associated Pathogenicity in Chronic Intestinal Inflammation

BACKGROUND & AIMS: Incapacitated regulatory T cells (Tregs) contribute to immune-mediated diseases. Inflammatory Tregs are evident during human inflammatory bowel disease (IBD); however, mechanisms driving the development of these cells and their function are not well understood. Therefore, we i...

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Detalles Bibliográficos
Autores principales: Bamidele, Adebowale O., Mishra, Shravan K., Hirsova, Petra, Fehrenbach, Patrick J., Valenzuela-Pérez, Lucia, Lee, Hyun Se Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274654/
https://www.ncbi.nlm.nih.gov/pubmed/37333332
http://dx.doi.org/10.1101/2023.06.02.543518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274654/
https://www.ncbi.nlm.nih.gov/pubmed/37333332
http://dx.doi.org/10.1101/2023.06.02.543518

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