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Interleukin-21 Drives a Hypermetabolic State and CD4(+) T Cell-associated Pathogenicity in Chronic Intestinal Inflammation
BACKGROUND & AIMS: Incapacitated regulatory T cells (Tregs) contribute to immune-mediated diseases. Inflammatory Tregs are evident during human inflammatory bowel disease (IBD); however, mechanisms driving the development of these cells and their function are not well understood. Therefore, we i...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274654/ https://www.ncbi.nlm.nih.gov/pubmed/37333332 http://dx.doi.org/10.1101/2023.06.02.543518 |