Engineering ligand stabilized aquaporin reporters for magnetic resonance imaging

Imaging transgene expression in live tissues requires reporters that are detectable with deeply penetrant modalities, such as magnetic resonance imaging (MRI). Here, we show that LSAqp1, a water channel engineered from aquaporin-1, can be used to create background-free, drug-gated, and multiplex ima...

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Detalles Bibliográficos
Autores principales: Yun, Jason, Baldini, Logan, Huang, Yimeng, Li, Eugene, Li, Honghao, Chacko, Asish N., Miller, Austin D.C., Wan, Jinyang, Mukherjee, Arnab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274688/
https://www.ncbi.nlm.nih.gov/pubmed/37333371
http://dx.doi.org/10.1101/2023.06.02.543364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274688/
https://www.ncbi.nlm.nih.gov/pubmed/37333371
http://dx.doi.org/10.1101/2023.06.02.543364

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