Amyloid β Induces Lipid Droplet-Mediated Microglial Dysfunction in Alzheimer’s Disease

Several microglia-expressed genes have emerged as top risk variants for Alzheimer’s disease (AD). Impaired microglial phagocytosis is one of the main proposed outcomes by which these AD-risk genes may contribute to neurodegeneration, but the mechanisms translating genetic association to cellular dys...

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Detalles Bibliográficos
Autores principales: Prakash, Priya, Manchanda, Palak, Paouri, Evi, Bisht, Kanchan, Sharma, Kaushik, Wijewardhane, Prageeth R., Randolph, Caitlin E., Clark, Matthew G., Fine, Jonathan, Thayer, Elizabeth A., Crockett, Alexis, Gasmi, Nadia, Stanko, Sarah, Prayson, Richard A., Zhang, Chi, Davalos, Dimitrios, Chopra, Gaurav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274698/
https://www.ncbi.nlm.nih.gov/pubmed/37333071
http://dx.doi.org/10.1101/2023.06.04.543525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274698/
https://www.ncbi.nlm.nih.gov/pubmed/37333071
http://dx.doi.org/10.1101/2023.06.04.543525

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