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Necessary Role of Acute Ceramide Formation in The Human Microvascular Endothelium During Health and Disease

BACKGROUND: Elevated plasma ceramides independently predict adverse cardiac events and we have previously shown that exposure to exogenous ceramide induces microvascular endothelial dysfunction in arterioles from otherwise healthy adults (0–1 risk factors for heart disease). However, evidence also s...

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Detalles Bibliográficos
Autores principales: SenthilKumar, Gopika, Katunaric, Boran, Zirgibel, Zachary, Lindemer, Brian, Jaramillo-Torres, Maria J., Bordas-Murphy, Henry, Schulz, Mary E., Pearson, Paul J., Freed, Julie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274701/
https://www.ncbi.nlm.nih.gov/pubmed/37333082
http://dx.doi.org/10.1101/2023.06.02.543341