Cargando…

Necessary Role of Acute Ceramide Formation in The Human Microvascular Endothelium During Health and Disease

BACKGROUND: Elevated plasma ceramides independently predict adverse cardiac events and we have previously shown that exposure to exogenous ceramide induces microvascular endothelial dysfunction in arterioles from otherwise healthy adults (0–1 risk factors for heart disease). However, evidence also s...

Descripción completa

Detalles Bibliográficos
Autores principales:	SenthilKumar, Gopika, Katunaric, Boran, Zirgibel, Zachary, Lindemer, Brian, Jaramillo-Torres, Maria J., Bordas-Murphy, Henry, Schulz, Mary E., Pearson, Paul J., Freed, Julie K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274701/ https://www.ncbi.nlm.nih.gov/pubmed/37333082 http://dx.doi.org/10.1101/2023.06.02.543341

Ejemplares similares

17β-Estradiol promotes sex-specific dysfunction in isolated human arterioles
por: SenthilKumar, Gopika, et al.
Publicado: (2023)

Role of Adiponectin Receptor 1 in Promoting Nitric Oxide-Mediated Flow-Induced Dilation in the Human Microvasculature
por: Cohen, Katie E., et al.
Publicado: (2022)

Targeted Cardiac Ionizing Radiation in Dahl Salt-Sensitive Rats Can Improve Recovery From Ischemic Injury
por: SenthilKumar, Gopika, et al.
Publicado: (2023)

Lactate Dehydrogenase A Expression Is Necessary to Sustain Rapid Angiogenesis of Pulmonary Microvascular Endothelium
por: Parra-Bonilla, Glenda, et al.
Publicado: (2013)

Blockade of endothelial Mas receptor restores the vasomotor response to phenylephrine in human resistance arterioles pretreated with captopril and exposed to propofol
por: Schulz, Mary E., et al.
Publicado: (2022)

Manipulation of the Sphingolipid Rheostat Influences the Mediator of Flow‐Induced Dilation in the Human Microvasculature
por: Schulz, Mary E., et al.
Publicado: (2019)

Endothelium in Coronary Macrovascular and Microvascular Diseases
por: Godo, Shigeo, et al.
Publicado: (2021)

Ceramides are necessary and sufficient for diet-induced impairment of thermogenic adipocytes
por: Chaurasia, Bhagirath, et al.
Publicado: (2020)

Insights on supporting the aging brain microvascular endothelium
por: Barabutis, Nektarios
Publicado: (2021)

Inflammatory Response in Microvascular Endothelium in Sepsis: Role of Oxidants
por: Cepinskas, Gediminas, et al.
Publicado: (2008)

Influenza Infects Lung Microvascular Endothelium Leading to Microvascular Leak: Role of Apoptosis and Claudin-5
por: Armstrong, Susan M., et al.
Publicado: (2012)

Analysis of Physiologic E-Selectin-Mediated Leukocyte Rolling on Microvascular Endothelium
por: Wiese, Georg, et al.
Publicado: (2009)

Marked elevations in lung and plasma ceramide in COVID-19 linked to microvascular injury
por: Petrache, Irina, et al.
Publicado: (2023)

Advances in Preclinical Research Models of Radiation-Induced Cardiac Toxicity
por: Schlaak, Rachel A., et al.
Publicado: (2020)

Particulate Matter Exposure Impairs Systemic Microvascular Endothelium-Dependent Dilation
por: Nurkiewicz, Timothy R., et al.
Publicado: (2004)

MicroRNA Signature of Human Microvascular Endothelium Infected with Rickettsia rickettsii
por: Sahni, Abha, et al.
Publicado: (2017)

Effects of Hyperoxia and Hyperoxic Oscillations on the Proteome of Murine Lung Microvascular Endothelium
por: Tiboldi, Akos, et al.
Publicado: (2022)

Microvascular Environment Influences Brain Microvascular Heterogeneity: Relative Roles of Astrocytes and Oligodendrocytes for the EPCR Expression in the Brain Endothelium
por: Thakar, Manjusha, et al.
Publicado: (2023)

VE-Cadherin Disassembly and Cell Contractility in the Endothelium are Necessary for Barrier Disruption Induced by Tumor Cells
por: Aragon-Sanabria, Virginia, et al.
Publicado: (2017)

Molecular Insights into the Thrombotic and Microvascular Injury in Placental Endothelium of Women with Mild or Severe COVID-19
por: Flores-Pliego, Arturo, et al.
Publicado: (2021)

The Pleiotropic Effects of Simvastatin on Retinal Microvascular Endothelium Has Important Implications for Ischaemic Retinopathies
por: Medina, Reinhold J., et al.
Publicado: (2008)

Diabetic Retinopathy Is Related to Both Endothelium-Dependent and -Independent Responses of Skin Microvascular Flow
por: Nguyen, Thanh T., et al.
Publicado: (2011)

Hyperglycemia and Diabetes Downregulate the Functional Expression of TRPV4 Channels in Retinal Microvascular Endothelium
por: Monaghan, Kevin, et al.
Publicado: (2015)

The Brain Microvascular Endothelium Supports T Cell Proliferation and Has Potential for Alloantigen Presentation
por: Wheway, Julie, et al.
Publicado: (2013)

Tagged Halloysite Nanotubes as a Carrier for Intercellular Delivery in Brain Microvascular Endothelium
por: Saleh, Mahdi Yar, et al.
Publicado: (2020)

Hsp90 inhibition protects the brain microvascular endothelium against oxidative stress
por: Uddin, Mohammad A., et al.
Publicado: (2021)

Lower endothelium-dependent microvascular function in adult breast cancer patients receiving radiation therapy
por: Banister, Heather R., et al.
Publicado: (2021)

670nm photobiomodulation modulates bioenergetics and oxidative stress, in rat Müller cells challenged with high glucose
por: Nonarath, Hannah J., et al.
Publicado: (2021)

NOX2 and NOX5 are increased in cardiac microvascular endothelium of deceased COVID-19 patients
por: Jiang, Zhu, et al.
Publicado: (2023)

Small Interfering RNA Efficiently Suppresses Adhesion Molecule Expression on Pulmonary Microvascular Endothelium
por: Walker, Tobias, et al.
Publicado: (2011)

Correction: The Brain Microvascular Endothelium Supports T Cell Proliferation and Has Potential for Alloantigen Presentation
por: Wheway, Julie, et al.
Publicado: (2013)

Cultivation of Human Microvascular Endothelial Cells on Topographical Substrates to Mimic the Human Corneal Endothelium
por: Chua, Jie Shi, et al.
Publicado: (2013)

Editorial: Cardiac Microvascular Endothelium Contribution to Cardiac Myocyte Growth, Structure, and Contractile Function
por: Altara, Raffaele, et al.
Publicado: (2019)

Proteomics Analysis Reveals Diverse Molecular Characteristics between Endocardial and Aortic-Valvular Endothelium
por: Aneesh Kumar, A., et al.
Publicado: (2021)

Identification of homing peptides specific for synovial microvascular endothelium using in vivo phage display selection
por: Lee, L, et al.
Publicado: (2002)

Gestational Diabetes Reduces Adenosine Transport in Human Placental Microvascular Endothelium, an Effect Reversed by Insulin
por: Salomón, Carlos, et al.
Publicado: (2012)

Tender Endothelium Syndrome: Combination of Hypotension, Bradycardia, Contrast Induced Chest Pain, and Microvascular Angina
por: Goberdhan, Shivesh, et al.
Publicado: (2016)

Rab5-mediated VE-cadherin internalization regulates the barrier function of the lung microvascular endothelium
por: Yang, Junjun, et al.
Publicado: (2015)

Ceramide and ceramide 1-phosphate in health and disease
por: Arana, Lide, et al.
Publicado: (2010)

Intracellular trafficking of ceramide by ceramide transfer protein
por: Hanada, Kentaro
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_m56seosc9e7se8n2g6oqhuqk4o