Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 hours

Disruption of pancreatic islet function and glucose homeostasis can lead to the development of sustained hyperglycemia, beta cell glucotoxicity, and ultimately type 2 diabetes (T2D). In this study, we sought to explore the effects of hyperglycemia on human pancreatic islet (HPI) gene expression by e...

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Detalles Bibliográficos
Autores principales: Grenko, Caleb M., Bonnycastle, Lori L., Taylor, Henry J., Yan, Tingfen, Swift, Amy J., Robertson, Catherine C., Narisu, Narisu, Erdos, Michael R., Collins, Francis S., Taylor, D. Leland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274787/
https://www.ncbi.nlm.nih.gov/pubmed/37333221
http://dx.doi.org/10.1101/2023.06.06.543931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274787/
https://www.ncbi.nlm.nih.gov/pubmed/37333221
http://dx.doi.org/10.1101/2023.06.06.543931

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