IL-22 promotes acute kidney injury through activation of the DNA damage response and cell death in proximal tubule cells

Acute kidney injury (AKI) affects over 13 million people world-wide annually and is associated with a fourfold increase in mortality. Our lab and others have shown that DNA damage response (DDR) governs the outcome of AKI in a bimodal manner. Activation of DDR sensor kinases protects against AKI, wh...

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Detalles Bibliográficos
Autores principales: Taguchi, Kensei, Sugahara, Sho, Elias, Bertha C., Pabla, Navjot, Canaud, Guillaume, Brooks, Craig R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274795/
https://www.ncbi.nlm.nih.gov/pubmed/37333314
http://dx.doi.org/10.1101/2023.06.08.544134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274795/
https://www.ncbi.nlm.nih.gov/pubmed/37333314
http://dx.doi.org/10.1101/2023.06.08.544134

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