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Quorum-sensing agr system of Staphylococcus aureus primes gene expression for protection from lethal oxidative stress

The agr quorum-sensing system links Staphylococcus aureus metabolism to virulence, in part by increasing bacterial survival during exposure to lethal concentrations of H(2)O(2), a crucial host defense against S. aureus. We now report that protection by agr surprisingly extends beyond post-exponentia...

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Detalles Bibliográficos
Autores principales: Podkowik, Magdalena, Perault, Andrew I., Putzel, Gregory, Pountain, Andrew, Kim, Jisun, Dumont, Ashley, Zwack, Erin, Ulrich, Robert J., Karagounis, Theodora K., Zhou, Chunyi, Haag, Andreas F., Shenderovich, Julia, Wasserman, Gregory A., Kwon, Junbeom, Chen, John, Richardson, Anthony R., Weiser, Jeffrey N., Nowosad, Carla R., Lun, Desmond S., Parker, Dane, Pironti, Alejandro, Zhao, Xilin, Drlica, Karl, Yanai, Itai, Torres, Victor J., Shopsin, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274873/
https://www.ncbi.nlm.nih.gov/pubmed/37333372
http://dx.doi.org/10.1101/2023.06.08.544038