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A spatial map of hepatic mitochondria uncovers functional heterogeneity shaped by nutrient-sensing signaling

In the liver, mitochondria are exposed to different concentrations of nutrients due to their spatial positioning across the periportal (PP) and pericentral (PC) axis. How these mitochondria sense and integrate these signals to respond and maintain homeostasis is not known. Here, we combined intravit...

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Detalles Bibliográficos
Autores principales: Kang, Sun Woo Sophie, Cunningham, Rory P., Miller, Colin B., Brown, Lauryn A., Cultraro, Constance M., Harned, Adam, Narayan, Kedar, Hernandez, Jonathan, Jenkins, Lisa M., Lobanov, Alexei, Cam, Maggie, Porat-Shliom, Natalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274915/
https://www.ncbi.nlm.nih.gov/pubmed/37333328
http://dx.doi.org/10.1101/2023.04.13.536717