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Site-Specific Phosphorylation of ZYG-1 Regulates ZYG-1 Stability and Centrosome Number

Spindle bipolarity is critical for genomic integrity. Given that centrosome number often dictates mitotic bipolarity, tight control of centrosome assembly is vital for the fidelity of cell division. The kinase ZYG-1/Plk4 is a master centrosome factor that is integral for controlling centrosome numbe...

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Detalles Bibliográficos
Autores principales: Medley, Jeffrey C., Yim, Nahyun, DiPanni, Joseph, Sebou, Brandon, Shaffou, Blake, Cramer, Evan, Wu, Colin, Kabara, Megan, Song, Mi Hye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274923/
https://www.ncbi.nlm.nih.gov/pubmed/37333374
http://dx.doi.org/10.1101/2023.05.07.539463