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Punishment resistance for cocaine is associated with inflexible habits in rats

Addiction is characterized by continued drug use despite negative consequences. In an animal model, a subset of rats continues to self-administer cocaine despite footshock consequences, showing punishment resistance. We sought to test the hypothesis that punishment resistance arises from failure to...

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Detalles Bibliográficos
Autores principales: Jones, Bradley O., Paladino, Morgan S., Cruz, Adelis M., Spencer, Haley F., Kahanek, Payton L., Scarborough, Lauren N., Georges, Sandra F., Smith, Rachel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274925/
https://www.ncbi.nlm.nih.gov/pubmed/37333299
http://dx.doi.org/10.1101/2023.06.08.544242