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Scalable telomere-to-telomere assembly for diploid and polyploid genomes with double graph

Despite recent advances in the length and the accuracy of long-read data, building haplotype-resolved genome assemblies from telomere to telomere still requires considerable computational resources. In this study, we present an efficient de novo assembly algorithm that combines multiple sequencing t...

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Detalles Bibliográficos
Autores principales: Cheng, Haoyu, Asri, Mobin, Lucas, Julian, Koren, Sergey, Li, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cornell University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274930/
https://www.ncbi.nlm.nih.gov/pubmed/37332563