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Rapid and Multiplexed Nucleic Acid Detection using Programmable Aptamer-Based RNA Switches

Rapid, simple, and low-cost diagnostic technologies are crucial tools for combatting infectious disease. Here, we describe a class of aptamer-based RNA switches called aptaswitches that recognize specific target nucleic acid molecules and respond by initiating folding of a reporter aptamer. Aptaswit...

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Detalles Bibliográficos
Autores principales: Yan, Zhaoqing, Tang, Anli A., Eshed, Amit, Ticktin, Zackary M., Chaudhary, Soma, Ma, Duo, McCutcheon, Griffin, Li, Yudan, Wu, Kaiyue, Saha, Sanchari, Alcantar-Fernandez, Jonathan, Moreno-Camacho, Jose L., Campos-Romero, Abraham, Collins, James J., Yin, Peng, Green, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275000/
https://www.ncbi.nlm.nih.gov/pubmed/37333364
http://dx.doi.org/10.1101/2023.06.02.23290873