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Human alveolar macrophage response to Mycobacterium tuberculosis: immune characteristics underlying large inter-individual variability

BACKGROUND: Mycobacterium tuberculosis (M.tb), the causative bacterium of tuberculosis (TB), establishes residence and grows in human alveolar macrophages (AMs). Inter-individual variation in M.tb-human AM interactions can indicate TB risk and the efficacy of therapies and vaccines; however, we curr...

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Detalles Bibliográficos
Autores principales: Sadee, Wolfgang, Cheeseman, Ian H., Papp, Audrey, Pietrzak, Maciej, Seweryn, Michal, Zhou, Xiaofei, Lin, Shili, Williams, Amanda M., Wewers, Mark D., Curry, Heather M., Zhang, Hao, Cai, Hong, Kunsevi-Kilola, Carine, Tshivhula, Happy, Walzl, Gerhard, Restrepo, Blanca I., Kleynhans, Léanie, Ronacher, Katharina, Wang, Yufeng, Arnett, Eusondia, Azad, Abul K., Schlesinger, Larry S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275041/
https://www.ncbi.nlm.nih.gov/pubmed/37333188
http://dx.doi.org/10.21203/rs.3.rs-2986649/v1