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Behavioral and metabolic and effects of ABCG4 KO in the APPswe,Ind (J9) mouse model of Alzheimer’s disease

The pathogenesis of Alzheimer’s disease (AD) is complex and involves an imbalance between production and clearance of amyloid-ß peptides (Aß), resulting in accumulation of Aß in senile plaques. Hypercholesterolemia is a major risk factor for developing AD, with cholesterol shown to accumulate in sen...

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Detalles Bibliográficos
Autores principales: Fong, Vincent, Kanuri, Babunageswararao, Traubert, Owen, Lui, Min, Patel, Shailendra B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275060/
https://www.ncbi.nlm.nih.gov/pubmed/37333297
http://dx.doi.org/10.21203/rs.3.rs-3014093/v1