bakR: uncovering differential RNA synthesis and degradation kinetics transcriptome-wide with Bayesian hierarchical modeling

Differential expression analysis of RNA sequencing (RNA-seq) data can identify changes in cellular RNA levels, but provides limited information about the kinetic mechanisms underlying such changes. Nucleotide recoding RNA-seq methods (NR-seq; e.g., TimeLapse-seq, SLAM-seq, etc.) address this shortco...

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Detalles Bibliográficos
Autores principales: Vock, Isaac W., Simon, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275263/
https://www.ncbi.nlm.nih.gov/pubmed/37028916
http://dx.doi.org/10.1261/rna.079451.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275263/
https://www.ncbi.nlm.nih.gov/pubmed/37028916
http://dx.doi.org/10.1261/rna.079451.122

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