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Co-phase separation of Y14 and RNA in vitro and its implication for DNA repair

The multifunctional RNA recognition motif-containing protein Y14/RBM8A participates in mRNA metabolism and is essential for the efficient repair of DNA double-strand breaks (DSBs). Y14 contains highly charged, low-complexity sequences in both the amino- and carboxy-terminal domains. The feature of c...

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Detalles Bibliográficos
Autores principales: Yu, Chia-Lin, Chuang, Tzu-Wei, Samuel, Sabrina Yeo, Lou, Yuan-Chao, Tarn, Woan-Yuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275266/
https://www.ncbi.nlm.nih.gov/pubmed/37001915
http://dx.doi.org/10.1261/rna.079514.122