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GLP-1 receptor agonists as promising disease-modifying agents in WFS1 spectrum disorder

WFS1 spectrum disorder (WFS1-SD) is a rare monogenic neurodegenerative disorder whose cardinal symptoms are childhood-onset diabetes mellitus, optic atrophy, deafness, diabetes insipidus, and neurological signs ranging from mild to severe. The prognosis is poor as most patients die prematurely with...

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Detalles Bibliográficos
Autores principales: Panfili, Eleonora, Frontino, Giulio, Pallotta, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275359/
https://www.ncbi.nlm.nih.gov/pubmed/37333802
http://dx.doi.org/10.3389/fcdhc.2023.1171091