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The Long Noncoding RNA H19 Promotes Fibrotic Processes in Lens Epithelial Cells

PURPOSE: The purpose of this study was to investigate the role of lncRNA H19 in epithelial-mesenchymal transition (EMT) and its molecular mechanism in fibrotic cataracts. METHODS: TGF-β2-induced EMT was induced in human lens epithelial cell line (HLECs) and rat lens explants to mimic posterior capsu...

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Detalles Bibliográficos
Autores principales: Li, Hanrong, Ji, Liyang, Shen, Haoyue, Guo, Zhuo, Qin, Yu, Feng, Li, Zhao, Jiangyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275388/
https://www.ncbi.nlm.nih.gov/pubmed/37310354
http://dx.doi.org/10.1167/iovs.64.7.21