TNF licenses macrophages to undergo rapid caspase-1, -11, and -8-mediated cell death that restricts Legionella pneumophila infection

The inflammatory cytokine tumor necrosis factor (TNF) is necessary for host defense against many intracellular pathogens, including Legionella pneumophila. Legionella causes the severe pneumonia Legionnaires’ disease and predominantly affects individuals with a suppressed immune system, including th...

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Detalles Bibliográficos
Autores principales: Pollock, Tzvi Y., Vázquez Marrero, Víctor R., Brodsky, Igor E., Shin, Sunny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275475/
https://www.ncbi.nlm.nih.gov/pubmed/37279255
http://dx.doi.org/10.1371/journal.ppat.1010767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275475/
https://www.ncbi.nlm.nih.gov/pubmed/37279255
http://dx.doi.org/10.1371/journal.ppat.1010767

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