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Mathematical properties of optimal fluxes in cellular reaction networks at balanced growth

The physiology of biological cells evolved under physical and chemical constraints, such as mass conservation across the network of biochemical reactions, nonlinear reaction kinetics, and limits on cell density. For unicellular organisms, the fitness that governs this evolution is mainly determined...

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Detalles Bibliográficos
Autores principales: Dourado, Hugo, Liebermeister, Wolfram, Ebenhöh, Oliver, Lercher, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275479/
https://www.ncbi.nlm.nih.gov/pubmed/37279246
http://dx.doi.org/10.1371/journal.pcbi.1011156