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Discovery of PL(pro) and M(pro) Inhibitors for SARS-CoV-2

[Image: see text] There are very few small-molecule antivirals for SARS-CoV-2 that are either currently approved (or emergency authorized) in the US or globally, including remdesivir, molnupiravir, and paxlovid. The increasing number of SARS-CoV-2 variants that have appeared since the outbreak began...

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Detalles Bibliográficos
Autores principales: Puhl, Ana C., Godoy, Andre S., Noske, Gabriela D., Nakamura, Aline M., Gawriljuk, Victor O., Fernandes, Rafaela S., Oliva, Glaucius, Ekins, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275482/
https://www.ncbi.nlm.nih.gov/pubmed/37387790
http://dx.doi.org/10.1021/acsomega.3c01110