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Unsaturated free fatty acid emulsion infusion into carotid artery enhances drug delivery to the rat brain
AIMS: : To determine whether the blood–brain barrier (BBB) opens to enhance drug delivery during the acute stage of unsaturated fat embolism. METHODS: : We infused oleic, linoleic, and linolenic acid emulsions through the right common carotid artery of rats, followed by trypan blue for gross and lan...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275518/ https://www.ncbi.nlm.nih.gov/pubmed/37218399 http://dx.doi.org/10.1002/brb3.2994 |