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Unsaturated free fatty acid emulsion infusion into carotid artery enhances drug delivery to the rat brain

AIMS: : To determine whether the blood–brain barrier (BBB) opens to enhance drug delivery during the acute stage of unsaturated fat embolism. METHODS: : We infused oleic, linoleic, and linolenic acid emulsions through the right common carotid artery of rats, followed by trypan blue for gross and lan...

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Detalles Bibliográficos
Autores principales: Kim, Yong‐Woo, Choi, Seon Hee, Choi, Ki Joo, Kim, Hak Jin, Kang, Jin Sook, Hong, Dong Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275518/
https://www.ncbi.nlm.nih.gov/pubmed/37218399
http://dx.doi.org/10.1002/brb3.2994