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Cord blood–derived V(δ)2(+) and V(δ)2(−) T cells acquire differential cell state compositions upon in vitro expansion

Human cord blood–derived γδ T cells (CB(γδ)) display a highly diverse TCR(γδ) repertoire and have a unique subtype composition different from fetal or adult peripheral blood counterparts. We expanded CB(γδ) in vitro using an irradiated Epstein-Barr virus–transformed feeder cell–based modified rapid...

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Detalles Bibliográficos
Autores principales: Ng, Jeremy Wee Kiat, Tan, Kar Wai, Guo, Dian Yan, Lai, Joey Jia Hui, Fan, Xiubo, Poon, Zhiyong, Lim, Tse Hui, Lim, Alvin Soon Tiong, Lim, Tony Kiat Hon, Hwang, William Ying Khee, Li, Shang, Eaves, Connie J., Goh, Yeow Tee, Cheung, Alice Man Sze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275585/
https://www.ncbi.nlm.nih.gov/pubmed/37327346
http://dx.doi.org/10.1126/sciadv.adf3120