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The temporal balance between self-renewal and differentiation of human neural stem cells requires the amyloid precursor protein

Neurogenesis in the developing human cerebral cortex occurs at a particularly slow rate owing in part to cortical neural progenitors preserving their progenitor state for a relatively long time, while generating neurons. How this balance between the progenitor and neurogenic state is regulated, and...

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Detalles Bibliográficos
Autores principales: Shabani, Khadijeh, Pigeon, Julien, Benaissa Touil Zariouh, Marwan, Liu, Tengyuan, Saffarian, Azadeh, Komatsu, Jun, Liu, Elise, Danda, Natasha, Becmeur-Lefebvre, Mathilde, Limame, Ridha, Bohl, Delphine, Parras, Carlos, Hassan, Bassem A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275593/
https://www.ncbi.nlm.nih.gov/pubmed/37327344
http://dx.doi.org/10.1126/sciadv.add5002