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Single-cell and spatial transcriptome analysis reveals the cellular heterogeneity of liver metastatic colorectal cancer

In this study, we comprehensively charted the cellular landscape of colorectal cancer (CRC) and well-matched liver metastatic CRC using single-cell and spatial transcriptome RNA sequencing. We generated 41,892 CD45(−) nonimmune cells and 196,473 CD45(+) immune cells from 27 samples of six CRC patien...

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Detalles Bibliográficos
Autores principales: Wang, Fei, Long, Jie, Li, Liang, Wu, Zi-Xin, Da, Tian-Tian, Wang, Xiao-Qing, Huang, Chuan, Jiang, Yi-Hua, Yao, Xue-Qing, Ma, Hai-Qing, Lian, Zhe-Xiong, Zhao, Zhi-Bin, Cao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275599/
https://www.ncbi.nlm.nih.gov/pubmed/37327339
http://dx.doi.org/10.1126/sciadv.adf5464