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Unique features of the TCR repertoire of reactivated memory T cells in the experimental mouse tumor model

T cell engineering with T cell receptors (TCR) specific to tumor antigens has become a breakthrough towards personalized cancer adoptive cell immunotherapy. However, the search for therapeutic TCRs is often challenging, and effective strategies are strongly required for the identification and enrich...

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Detalles Bibliográficos
Autores principales: Kalinina, Anastasiia, Persiyantseva, Nadezda, Britanova, Olga, Lupyr, Ksenia, Shagina, Irina, Khromykh, Ludmila, Kazansky, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275742/
https://www.ncbi.nlm.nih.gov/pubmed/37333858
http://dx.doi.org/10.1016/j.csbj.2023.05.028