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M6A modification promotes blood-brain barrier breakdown during cerebral ischemia/reperfusion injury through increasing matrix metalloproteinase 3 expression

Blood-brain barrier (BBB) breakdown is a critical event in cerebral ischemia-reperfusion (I/R) injury, and matrix metalloproteinases (MMPs), which are proteolytic enzymes, play essential roles in BBB breakdown through degrading the extracellular matrix. N6-Methyladenosine (m6A), the most common and...

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Detalles Bibliográficos
Autores principales: Liang, En, Xiao, Shaorong, Zhao, Changtong, Zhang, Yu, Fu, Guanglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275791/
https://www.ncbi.nlm.nih.gov/pubmed/37332938
http://dx.doi.org/10.1016/j.heliyon.2023.e16905