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Single cell profiling of female breast fibroadenoma reveals distinct epithelial cell compositions and therapeutic targets

Fibroadenomas (FAs) are the most common breast tumors in women. No pharmacological agents are currently approved for FA intervention owing to its unclear mechanisms and a shortage of reproducible human models. Here, using single-cell RNA sequencing of human FAs and normal breast tissues, we observe...

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Detalles Bibliográficos
Autores principales: Chen, Zhigang, Zhang, Yi, Li, Wenlu, Gao, Chenyi, Huang, Fengbo, Cheng, Lu, Jin, Menglei, Xu, Xiaoming, Huang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275980/
https://www.ncbi.nlm.nih.gov/pubmed/37328469
http://dx.doi.org/10.1038/s41467-023-39059-3