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Sinapic acid alleviates 5-fluorouracil-induced nephrotoxicity in rats via Nrf2/HO-1 signalling

Fluoropyrimidine 5-fluorouracil (5-FU) is a DNA analogue broadly used in chemotherapy, though treatment-associated nephrotoxicity limits its widespread clinical use. Sinapic acid (SA) has potent antioxidant, anti-inflammatory, and anti-apoptotic effects, we investigated its protective effects agains...

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Detalles Bibliográficos
Autores principales: Ahmad Ansari, Mushtaq, Shahid, Mudassar, Ahmad, Sheikh F., Ahmad, Ajaz, Alanazi, Abdulrazaq, Malik, Abdul, Bin Jardan, Yousef A., Attia, Sabry M., Bakheet, Saleh A., Raish, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275981/
https://www.ncbi.nlm.nih.gov/pubmed/37333019
http://dx.doi.org/10.1016/j.jsps.2023.05.021