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Targeted viral adaptation generates a simian-tropic hepatitis B virus that infects marmoset cells

Hepatitis B virus (HBV) only infects humans and chimpanzees, posing major challenges for modeling HBV infection and chronic viral hepatitis. The major barrier in establishing HBV infection in non-human primates lies at incompatibilities between HBV and simian orthologues of the HBV receptor, sodium...

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Detalles Bibliográficos
Autores principales: Liu, Yongzhen, Cafiero, Thomas R., Park, Debby, Biswas, Abhishek, Winer, Benjamin Y., Cho, Cheul H., Bram, Yaron, Chandar, Vasuretha, Connell, Aoife K. O’, Gertje, Hans P., Crossland, Nicholas, Schwartz, Robert E., Ploss, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276007/
https://www.ncbi.nlm.nih.gov/pubmed/37328459
http://dx.doi.org/10.1038/s41467-023-39148-3