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Defining an optimal control for RNAi experiments with adult Schistosoma mansoni

In parasites such as Schistosoma mansoni, gene knockdown by RNA interference (RNAi) has become an indispensable tool for functional gene characterization. To distinguish target-specific RNAi effects versus off-target effects, controls are essential. To date, however, there is still no general agreem...

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Detalles Bibliográficos
Autores principales: Moescheid, Max F., Puckelwaldt, Oliver, Beutler, Mandy, Haeberlein, Simone, Grevelding, Christoph G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276032/
https://www.ncbi.nlm.nih.gov/pubmed/37328492
http://dx.doi.org/10.1038/s41598-023-36826-6