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TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway

T-LAK-originated protein kinase (TOPK), a dual specificity serine/threonine kinase, is up-regulated and related to poor prognosis in many types of cancers. Y-box binding protein 1 (YB1) is a DNA/RNA binding protein and serves important roles in multiple cellular processes. Here, we reported that TOP...

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Detalles Bibliográficos
Autores principales: Wu, Wenjie, Xu, Jialuo, Gao, Dan, Xie, Zhenliang, Chen, Wenjing, Li, Wenjing, Yuan, Qiang, Duan, Lina, Zhang, Yuhan, Yang, Xiaoxiao, Chen, Yingying, Dong, Ziming, Liu, Kangdong, Jiang, Yanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276051/
https://www.ncbi.nlm.nih.gov/pubmed/37328464
http://dx.doi.org/10.1038/s41419-023-05883-0