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Loss of Heterozygosity and Its Importance in Evolution
Loss of heterozygosity (LOH) is a mitotic recombination event that converts heterozygous loci to homozygous loci. This mutation event is widespread in organisms that have asexual reproduction like budding yeasts, and is also an important and frequent mutation event in tumorigenesis. Mutation accumul...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276065/ https://www.ncbi.nlm.nih.gov/pubmed/36752826 http://dx.doi.org/10.1007/s00239-022-10088-8 |